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1

Role of Oxidative Stress in Peroxisome Proliferator-Mediated Carcinogenesis

O'Brien, Michelle L., Spear, Brett T., Glauert, Howard P.

Journal:

Critical Reviews in Toxicology

Year:

2005

Language:

english

File:

PDF, 2.54 MB

english, 2005

2

The oncofetal gene glypican 3 is regulated in the postnatal liver by zinc fingers and homeoboxes 2 and in the regenerating liver by alpha-fetoprotein regulator 2

Lorri A. Morford, Christina Davis, Lin Jin, Aneta Dobierzewska, Martha L. Peterson, Brett T. Spear

Journal:

Year:

2007

Language:

english

File:

PDF, 531 KB

english, 2007

3

Effect of a single dose of polychlorinated biphenyls on hepatic cell proliferation and the DNA binding activity of NF-κB and AP-1 in rats

Zijing Lu, Job C. Tharappel, Eun Y. Lee, Larry W. Robertson, Brett T. Spear, Howard P. Glauert

Journal:

Molecular Carcinogenesis

Year:

2003

Language:

english

File:

PDF, 276 KB

english, 2003

4

Dietary antioxidants in the prevention of hepatocarcinogenesis: A review

Howard P. Glauert, Karen Calfee-Mason, Divinia N. Stemm, Job C. Tharappel, Brett T. Spear

Journal:

Molecular Nutrition & Food Research

Year:

2010

Language:

english

File:

PDF, 222 KB

english, 2010

5

The effect of dietary glycine on the hepatic tumor promoting activity of polychlorinated biphenyls (PCBs) in rats

Rodica Petruta Bunaciu, Job C. Tharappel, Hans-Joachim Lehmler, Izabela Kania-Korwel, Larry W. Robertson, Cidambi Srinivasan, Brett T. Spear, Howard P. Glauert

Journal:

Year:

2007

Language:

english

File:

PDF, 349 KB

english, 2007

6

Characterization of the ETnII-α endogenous retroviral element in the BALB/cJZhx2Afr1allele

Sudhir Perincheri, David K. Peyton, Michelle Glenn, Martha L. Peterson, Brett T. Spear

Journal:

Mammalian Genome

Year:

2008

Language:

english

File:

PDF, 328 KB

english, 2008

7

Increased Liver-specific Expression of Catalase in Transgenic Mice

VANI NILAKANTAN, YIXIN LI, BRETT T. SPEAR, HOWARD P. GLAUERT

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 658 KB

english, 1996

8

Mutation of a new sodium channel gene, Scn8a, in the mouse mutant ‘motor endplate disease’

Burgess, Daniel L., Kohrman, David C., Galt, James, Plummer, Nicholas W., Jones, Julie M., Spear, Brett, Meisler, Miriam H.

Journal:

Nature Genetics

Year:

1995

File:

PDF, 498 KB

1995

9

Alpha-fetoprotein gene regulation: lessons from transgenic mice

Journal:

Seminars in Cancer Biology

Year:

1999

Language:

english

File:

PDF, 320 KB

english, 1999

10

Effects of Peroxisome Proliferators on Glutathione and Glutathione-Related Enzymes in Rats and Hamsters

Michelle L. O'Brien, Michael L. Cunningham, Brett T. Spear, Howard P. Glauert

Journal:

Toxicology and Applied Pharmacology

Year:

2001

Language:

english

File:

PDF, 337 KB

english, 2001

11

Regulation of Cell Proliferation, Apoptosis, and Transcription Factor Activities during the Promotion of Liver Carcinogenesis by Polychlorinated Biphenyls

Job C. Tharappel, Eun Y. Lee, Larry W. Robertson, Brett T. Spear, Howard P. Glauert

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 521 KB

english, 2002

12

Endogenous and transfected mouse alpha-fetoprotein genes in undifferentiated F9 cells are activated in transient heterokaryons

Brett T. Spear, Amy W. Ellis

Journal:

Somatic Cell and Molecular Genetics

Year:

1995

Language:

english

File:

PDF, 1.45 MB

english, 1995

13

Lymphocyte function-associated antigen 1 (LFA-1) and natural killer (NK) cell activity: LFA-1 is not necessary for all killer:Target cell interactions

Mary Kate Hart, Jacki Kornbluth, Elliott K. Main, Brett T. Spear, Joan Taylor, Darcy B. Wilson

Journal:

Cellular Immunology

Year:

1987

Language:

english

File:

PDF, 1.01 MB

english, 1987

14

Zhx2 and Zbtb20: Novel regulators of postnatal alpha-fetoprotein repression and their potential role in gene reactivation during liver cancer

Martha L. Peterson, Chunhong Ma, Brett T. Spear

Journal:

Seminars in Cancer Biology

Year:

2011

Language:

english

File:

PDF, 376 KB

english, 2011

15

Effects of vitamin E on the NF-κB pathway in rats treated with the peroxisome proliferator, ciprofibrate

Karen G Calfee-Mason, Brett T Spear, Howard P Glauert

Journal:

Toxicology and Applied Pharmacology

Year:

2004

Language:

english

File:

PDF, 336 KB

english, 2004

16

Effect of phenobarbital on hepatic cell proliferation and apoptosis in mice deficient in the p50 subunit of NF-κB

Job C. Tharappel, Brett T. Spear, Howard P. Glauert

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 601 KB

english, 2008

17

Inhibition of the promotion of hepatocarcinogenesis by 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-κB in mice

Howard P. Glauert, Job C. Tharappel, Subhashis Banerjee, Nelson L.S. Chan, Izabela Kania-Korwel, Hans-Joachim Lehmler, Eun Y. Lee, Larry W. Robertson, Brett T. Spear

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 492 KB

english, 2008

18

Activation of nuclear factor-κB by the peroxisome proliferator ciprofibrate in H4IIEC3 rat hepatoma cells and its inhibition by the antioxidants N-acetylcysteine and vitamin E

Yixin Li, Howard P Glauert, Brett T Spear

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 400 KB

english, 2000

19

Effect of the Peroxisome Proliferator Ciprofibrate on Lipid Peroxidation and 8-Hydroxydeoxyguanosine Formation in Transgenic Mice with Elevated Hepatic Catalase Activity

Vani Nilakantan, Brett T Spear, Howard P Glauert

Journal:

Free Radical Biology and Medicine

Year:

1998

Language:

english

File:

PDF, 301 KB

english, 1998

20

Activation of Hepatic NF-κB by Phenobarbital in Rats

Yixin Li, Lai K. Leung, Brett T. Spear, Howard P. Glauert

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 215 KB

english, 1996

21

The Neuronal Voltage-Gated Sodium Channel, Scn8a, Is Essential for Postnatal Maturation of Spinal, but Not Oculomotor, Motor Units

John D. Porter, Linda A. Goldstein, Edward J. Kasarskis, Jennifer K. Brueckner, Brett T. Spear

Journal:

Experimental Neurology

Year:

1996

Language:

english

File:

PDF, 1.03 MB

english, 1996

22

The Alpha-fetoprotein Promoter Is the Target of Afr1-Mediated Postnatal Repression

David K. Peyton, Mei-Chuan Huang, Meredith A. Giglia, Nedda K. Hughes, Brett T. Spear

Journal:

Year:

2000

Language:

english

File:

PDF, 245 KB

english, 2000

23

Insertional mutation of the motor endplate disease (med) locus on mouse chromosome 15

David C. Kohrman, Nicholas W. Plummer, Timothy Schuster, Julie M. Jones, Wonhee Jang, Daniel L. Burgess, James Galt, Brett T. Spear, Miriam H. Meisler

Journal:

Year:

1995

Language:

english

File:

PDF, 908 KB

english, 1995

24

Role of oxidative stress in the promoting activities of PCBs

Howard P. Glauert, Job C. Tharappel, Zijing Lu, Divinia Stemm, Subhashis Banerjee, Lap Shun Chan, Eun Y. Lee, Hans-Joachim Lehmler, Larry W. Robertson, Brett T. Spear

Journal:

Environmental Toxicology and Pharmacology

Year:

2008

Language:

english

File:

PDF, 159 KB

english, 2008

25

Role of the p50 subunit of NF-κB in vitamin E-induced changes in mice treated with the peroxisome proliferator, ciprofibrate

Karen G. Calfee-Mason, Eun Y. Lee, Brett T. Spear, Howard P. Glauert

Journal:

Food and Chemical Toxicology

Year:

2008

Language:

english

File:

PDF, 465 KB

english, 2008

26

Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3′,4,4′-tetrachlorobiphenyl (PCB-77)

Job C. Tharappel, Hans-Joachim Lehmler, Cidambi Srinivasan, Larry W. Robertson, Brett T. Spear, Howard P. Glauert

Journal:

Food and Chemical Toxicology

Year:

2008

Language:

english

File:

PDF, 223 KB

english, 2008

27

Effect of vitamin E on hepatic cell proliferation and apoptosis in mice deficient in the p50 subunit of NF-κB after treatment with phenobarbital

Jun Li, Casey Harp, Job C. Tharappel, Brett T. Spear, Howard P. Glauert

Journal:

Food and Chemical Toxicology

Year:

2011

Language:

english

File:

PDF, 287 KB

english, 2011

28

Alpha-fetoprotein related gene (ARG): A new member of the albumin gene family that is no longer functional in primates

Sathyabama Naidu, Martha L. Peterson, Brett T. Spear

Journal:

Year:

2010

Language:

english

File:

PDF, 998 KB

english, 2010

29

The alpha-fetoprotein enhancer region activates the albumin and alpha-fetoprotein promoters during liver development

Lin Jin, Lingyun Long, Michael A. Green, Brett T. Spear

Journal:

Developmental Biology

Year:

2009

Language:

english

File:

PDF, 380 KB

english, 2009

30

Striking differences between the mouse and the human α-fetoprotein enhancers

Lingyun Long, Jeffrey N Davidson, Brett T Spear

Journal:

Year:

2004

Language:

english

File:

PDF, 913 KB

english, 2004

31

Pericentral activity of alpha-fetoprotein enhancer 3 and glutamine synthetase upstream enhancer in the adult liver are regulated by β-catenin in mice

Clinkenbeard, Erica L., Butler, James E., Spear, Brett T.

Journal:

Year:

2012

Language:

english

File:

PDF, 895 KB

english, 2012

32

Zinc Fingers and Homeoboxes 2 Inhibits Hepatocellular Carcinoma Cell Proliferation and Represses Expression of Cyclins A and E

Xuetian Yue, Zhenyu Zhang, Xiaohong Liang, Lifen Gao, Xiaoning Zhang, Di Zhao, Xiao Liu, Hongxin Ma, Min Guo, Brett T. Spear, Yaoqin Gong, Chunhong Ma

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 4.26 MB

english, 2012

33

PKI-587 and sorafenib alone and in combination on inhibition of liver cancer stem cell proliferation

Gedaly, Roberto, Galuppo, Roberto, Musgrave, Yolanda, Angulo, Paul, Hundley, Jonathan, Shah, Malay, Daily, Michael F., Chen, Changguo, Cohen, Donald A., Spear, Brett T., Evers, B. Mark

Journal:

Journal of Surgical Research

Year:

2013

Language:

english

File:

PDF, 637 KB

english, 2013

34

Indoor environmental quality benefits of apartment energy retrofits

Noris, Federico, Adamkiewicz, Gary, Delp, William W., Hotchi, Toshifumi, Russell, Marion, Singer, Brett C., Spears, Michael, Vermeer, Kimberly, Fisk, William J.

Journal:

Building and Environment

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

35

Effects of Cigarette Smoke on the Activation of Oxidative Stress-Related Transcription Factors in Female A/J Mouse Lung

Tharappel, Job C., Cholewa, Jill, Espandiari, Parvaneh, Spear, Brett T., Gairola, C. Gary, Glauert, Howard P.

Journal:

Journal of Toxicology and Environmental Health

Year:

2010

Language:

english

File:

PDF, 620 KB

english, 2010

36

The Mouse Alpha-Fetoprotein Promoter is Repressed in HepG2 Hepatoma Cells by Hepatocyte Nuclear Factor-3 (FOXA)

Huang, Mei-Chuan, Ke Li, Kelly, Spear, Brett T.

Journal:

DNA and Cell Biology

Year:

2002

Language:

english

File:

PDF, 402 KB

english, 2002

37

Increased Liver-Specific Catalase Activity in Transgenic Mice

NILAKANTAN, VANI, LI, YIXIN, GLAUERT, HOWARD P., SPEAR, BRETT T.

Journal:

DNA and Cell Biology

Year:

1996

Language:

english

File:

PDF, 3.17 MB

english, 1996

38

Expression of the Hydrogen Peroxide-Generating Enzyme Fatty Acyl CoA Oxidase Activates NF-kappa B

Li, Yixin, Tharappel, Job C., Cooper, Simon, Glenn, Michelle, Glauert, Howard P., Spear, Brett T.

Journal:

DNA and Cell Biology

Year:

2000

Language:

english

File:

PDF, 401 KB

english, 2000

39

A Sensitive lacZ -Based Expression Vector for Analyzing Transcriptional Control Elements in Eukaryotic Cells

SPEAR, BRETT T., LONGLEY, TRACY, MOULDER, SCOTT, WANG, STEPHEN L., PETERSON, MARTHA L.

Journal:

DNA and Cell Biology

Year:

1995

Language:

english

File:

PDF, 8.62 MB

english, 1995

40

The Mouse Alpha-Albumin (Afamin) Promoter Is Differentially Regulated by Hepatocyte Nuclear Factor 1α and Hepatocyte Nuclear Factor 1β

Liu, Hua, Ren, Hui, Spear, Brett T.

Journal:

DNA and Cell Biology

Year:

2011

Language:

english

File:

PDF, 709 KB

english, 2011

41

The History of the Church of York, 1066-1127.

Spear, David S., Hugh the Chanter,, Johnson, Charles, Brett, M., Brooke, C. N. L., Winterbottom, M.

Journal:

Year:

1993

Language:

english

File:

PDF, 263 KB

english, 1993

42

N-Aryl benzenesulfonamide inhibitors of [3H]-thymidine incorporation and β-catenin signaling in human hepatocyte-derived Huh-7 carcinoma cells

Kril, Liliia M., Vilchez, Valery, Jiang, Jieyun, Turcios, Lilia, Chen, Changguo, Sviripa, Vitaliy M., Zhang, Wen, Liu, Chunming, Spear, Brett, Watt, David S., Gedaly, Roberto

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 277 KB

english, 2015

43

Normal intestinal epithelial cell differentiation in the absence of p21 and p27: new insights from old knock-out mice

Butler, James E., Spear, Brett T.

Journal:

Cancer Biology & Therapy

Year:

2008

Language:

english

File:

PDF, 652 KB

english, 2008

44

Systemic Par-4 inhibits non-autochthonous tumor growth

Zhao, Yanming, Burikhanov, Ravshan, Brandon, Jason, Qiu, Shirley, Shelton, Brent J., Spear, Brett, Bondada, Subbarao, Bryson, Scott, Rangnekar, Vivek M.

Journal:

Cancer Biology & Therapy

Year:

2011

Language:

english

File:

PDF, 4.30 MB

english, 2011

45

Carbohydrate Differences in HLA-DR Molecules Synthesized by Alveolar Macrophages and Blood Monocytes 1–3

Ferro, Thomas J., Monos, Dimitri S., Spear, Brett T., Rossman, Milton D., Zmijewski, Chester M., Kamoun, Malek, Daniele, Ronald P.

Journal:

American Review of Respiratory Disease

Year:

1987

Language:

english

File:

PDF, 573 KB

english, 1987

46

A Nonimmunoglobulin Transgene and the Endogenous Immunoglobulin μ Gene Are Coordinately Regulated by Alternative RNA Processing during B-Cell Maturation

Seipelt, Rebecca L., Spear, Brett T., Snow, E. Charles, Peterson, Martha L.

Journal:

Molecular and Cellular Biology

Year:

1998

Language:

english

File:

PDF, 1.08 MB

english, 1998

47

ZBTB20 is a sequence-specific transcriptional repressor of alpha-fetoprotein gene

Zhang, Hai, Cao, Dongmei, Zhou, Luting, Zhang, Ye, Guo, Xiaoqin, Li, Hui, Chen, Yuxia, Spear, Brett T., Wu, Jia-Wei, Xie, Zhifang, Zhang, Weiping J.

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

48

Synergistic inhibition of HCC and liver cancer stem cell proliferation by targeting RAS/RAF/MAPK and WNT/??-Catenin pathways

Galuppo, Roberto, Maynard, Erin, Shah, Malay, Daily, Michael F., Chen, Changguo, Spear, Brett T., Gedaly, Roberto

Journal:

Anticancer research

Year:

2014

Language:

english

File:

PDF, 147 KB

english, 2014

49

Zhx2 (zinc fingers and homeoboxes 2) regulates major urinary protein gene expression in the mouse liver

Jiang, Jieyun, Creasy, Kate Townsend, Purnell, Justin, Peterson, Martha L., Spear, Brett T.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 5.73 MB

english, 2017

50

HBV suppresses ZHX2 expression to promote proliferation of HCC through miR-155 activation

Song, Xiaojia, Tan, Siyu, Wu, Zhuanchang, Xu, Leiqi, Wang, Zehua, Xu, Yong, Wang, Tixiao, Gao, Chengjiang, Gong, Yaoqin, Liang, Xiaohong, Gao, Lifen, Spear, Brett T., Ma, Chunhong

Journal:

International Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 1.70 MB

english, 2018

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